How you choose to structure your event is up to you. At the Coolidge, the guest scientist typically gives a 20–25 minute talk, followed by the film. Other theaters have opted to host a discussion, panel, and/or Q&A after the movie. Select the format that works best for your theater and audience.

For example, the California Film Institute presented a program called Physics and Fastballs at which a pair of experts on the science of baseball used clips from both science documentaries and Hollywood films The Natural and Bull Durham to examine the physics behind pitching, batting, and defense.

Event extras and "show and tell" elements can add another dimension to your programs. For example, a Coolidge Science on Screen event featuring Theremin: An Electronic Odyssey included a performance by a local thereminist. The State Theatre of Modesto's Robot and Frank program was preceded by demonstrations of a da Vinci surgical robot by local surgeons, among other activities. Following Athens Ciné's screening of Upstream Color and a talk on parasites, the theater hosted a reception where audience members learned about and sampled edible insects. Although the Cinefamily did not provide crickets for consumption, they did offer a live animal experience as part of one of their Science on Screen programs.

After a presentation of Bestiaire, a lyrical meditation on the relationship between humans and animals, and a Q&A with an animal social cognition expert, patrons were invited to observe a baby zebra and a pony (to keep the zebra calm) on the theater’s back patio. And when the State Theatre in Traverse City, Michigan, paired Twister with a talk on storm chasing, the speaker brought along instruments used by storm chasers around the world.